Pyrin domain-containing protein 1 (PYDC1)

About Pyrin domain-containing protein 1

Pyrin domain-containing protein 1 (PYDC1) is a protein from Homo sapiens identified by UniProt accession Q8WXC3, 89 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Pyrin domain-containing protein 1
UniProt accession	Q8WXC3
Gene	PYDC1
Organism	Homo sapiens
Length	89 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

smoking behaviour measurement · score 0.04
central nervous system cancer · score 0.03
apolipoprotein A 1 measurement · score 0.02
Behcet's syndrome · score 0.02
infection · score 0.01
infect · score 0.01
psoriasis · score 0.01
Thymoma · score 0.01
Rheumatoid arthritis · score 0.00
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WXC3-F1	alphafold	PREDICTED	89.01	—

Amino-acid sequence (89 residues)

MGTKREAILK VLENLTPEEL KKFKMKLGTV PLREGFERIP RGALGQLDIV DLTDKLVASY YEDYAAELVV AVLRDMRMLE EAARLQRAA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards