S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (RSAD2)

Homo sapiens — UniProt Q8WXG1

Gene: RSAD2Homo sapiensSwissProt reviewed

About S-adenosylmethionine-dependent nucleotide dehydratase RSAD2

S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (RSAD2) is a protein from Homo sapiens identified by UniProt accession Q8WXG1, 361 residues long. MolForge cross-references it against 0 known binders and 241 disease associations.

Target properties

Protein nameS-adenosylmethionine-dependent nucleotide dehydratase RSAD2
UniProt accessionQ8WXG1
GeneRSAD2
OrganismHomo sapiens
Length361 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (241)

Diseases linked to this target (Open Targets).

  • balding measurement · score 0.26
  • hair shape measurement · score 0.25
  • risk-taking behaviour · score 0.25
  • visual perception measurement · score 0.23
  • neurofibrillary tangles measurement · score 0.23
  • alopecia · score 0.20
  • androgenetic alopecia · score 0.19
  • disease progression measurement · score 0.18
  • metastasis measurement · score 0.18
  • breast milk measurement · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8WXG1-F1alphafoldPREDICTED87.36—

Amino-acid sequence (361 residues)

MWVLTPAAFA GKLLSVFRQP LSSLWRSLVP LFCWLRATFW LLATKRRKQQ LVLRGPDETK EEEEDPPLPT TPTSVNYHFT RQCNYKCGFC FHTAKTSFVL PLEEAKRGLL LLKEAGMEKI NFSGGEPFLQ DRGEYLGKLV RFCKVELRLP SVSIVSNGSL IRERWFQNYG EYLDILAISC DSFDEEVNVL IGRGQGKKNH VENLQKLRRW CRDYRVAFKI NSVINRFNVE EDMTEQIKAL NPVRWKVFQC LLIEGENCGE DALREAERFV IGDEEFERFL ERHKEVSCLV PESNQKMKDS YLILDEYMRF LNCRKGRKDP SKSILDVGVE EAIKFSGFDE KMFLKRGGKY IWSKADLKLD W

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Quick facts

UniProtQ8WXG1
GeneRSAD2
OrganismHomo sapiens
Length361
Binders0
Diseases241
View on UniProt