About BRI3-binding protein
BRI3-binding protein (BRI3BP) is a protein
from Homo sapiens identified by UniProt accession
Q8WY22, 251 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | BRI3-binding protein |
|---|
| UniProt accession | Q8WY22 |
|---|
| Gene | BRI3BP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 251 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.07
- liver disease · score 0.06
- urinary metabolite measurement · score 0.06
- lean body mass · score 0.02
- cancer · score 0.02
- lung adenocarcinoma · score 0.01
- neoplasm · score 0.01
- metastatic melanoma · score 0.01
- rosacea · score 0.01
- acne · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WY22-F1 | alphafold | PREDICTED | 62.81 | — |
Amino-acid sequence (251 residues)
MGARASGGPL ARAGLLLLLL LLLLLGLLAP GAQGARGRGG AEKNSYRRTV NTFSQSVSSL FGEDNVRAAQ KFLARLTERF VLGVDMFVET LWKVWTELLD VLGLDVSNLS QYFSPASVSS SPARALLLVG VVLLAYWFLS LTLGFTFSVL HVVFGRFFWI VRVVLFSMSC VYILHKYEGE PENAVLPLCF VVAVYFMTGP MGFYWRSSPS GPSNPSNPSV EEKLEHLEKQ VRLLNIRLNR VLESLDRSKD K
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