C-type lectin domain family 2 member B (CLEC2B)

About C-type lectin domain family 2 member B

C-type lectin domain family 2 member B (CLEC2B) is a protein from Homo sapiens identified by UniProt accession Q92478, 149 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

Target properties

Protein name	C-type lectin domain family 2 member B
UniProt accession	Q92478
Gene	CLEC2B
Organism	Homo sapiens
Length	149 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (53)

Diseases linked to this target (Open Targets).

inflammatory bowel disease · score 0.10
platelet crit · score 0.09
lymphocyte count · score 0.05
type 1 diabetes mellitus · score 0.04
platelet count · score 0.04
myxedema · score 0.03
neutrophil-to-lymphocyte ratio · score 0.03
hypothyroidism · score 0.03
neutrophil percentage of leukocytes · score 0.03
Thyroid preparation use measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92478-F1	alphafold	PREDICTED	92.22	—

Amino-acid sequence (149 residues)

MMTKHKKCFI IVGVLITTNI ITLIVKLTRD SQSLCPYDWI GFQNKCYYFS KEEGDWNSSK YNCSTQHADL TIIDNIEEMN FLRRYKCSSD HWIGLKMAKN RTGQWVDGAT FTKSFGMRGS EGCAYLSDDG AATARCYTER KWICRKRIH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards