Glycine N-acyltransferase-like protein 1 (GLYATL1)

About Glycine N-acyltransferase-like protein 1

Glycine N-acyltransferase-like protein 1 (GLYATL1) is a protein from Homo sapiens identified by UniProt accession Q969I3, 302 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Glycine N-acyltransferase-like protein 1
UniProt accession	Q969I3
Gene	GLYATL1
Organism	Homo sapiens
Length	302 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

cutaneous melanoma · score 0.26
lung adenocarcinoma · score 0.26
glioblastoma multiforme · score 0.16
squamous cell lung carcinoma · score 0.15
head and neck squamous cell carcinoma · score 0.15
mathematical ability · score 0.09
nonpapillary renal cell carcinoma · score 0.08
hepatocellular carcinoma · score 0.05
colorectal cancer · score 0.04
hypertrophic cardiomyopathy · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q969I3-F1	alphafold	PREDICTED	90.92	—

Amino-acid sequence (302 residues)

MILLNNSHKL LALYKSLARS IPESLKVYGS VYHINHGNPF NMEVLVDSWP EYQMVIIRPQ KQEMTDDMDS YTNVYRMFSK EPQKSEEVLK NCEIVNWKQR LQIQGLQESL GEGIRVATFS KSVKVEHSRA LLLVTEDILK LNASSKSKLG SWAETGHPDD EFESETPNFK YAQLDVSYSG LVNDNWKRGK NERSLHYIKR CIEDLPAACM LGPEGVPVSW VTMDPSCEVG MAYSMEKYRR TGNMARVMVR YMKYLRQKNI PFYISVLEEN EDSRRFVGQF GFFEASCEWH QWTCYPQNLV PF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards