About Synapse-associated protein 1
Synapse-associated protein 1 (SYAP1) is a protein
from Homo sapiens identified by UniProt accession
Q96A49, 352 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | Synapse-associated protein 1 |
|---|
| UniProt accession | Q96A49 |
|---|
| Gene | SYAP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 352 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.19
- infect · score 0.07
- infection · score 0.07
- benign prostatic hyperplasia · score 0.04
- lung adenocarcinoma · score 0.02
- neoplasm · score 0.02
- hepatocellular carcinoma · score 0.01
- Sepsis · score 0.01
- anxiety · score 0.00
- Intellectual disability · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96A49-F1 | alphafold | PREDICTED | 65.19 | — |
Amino-acid sequence (352 residues)
MFRGLSSWLG LQQPVAGGGQ PNGDAPPEQP SETVAESAEE ELQQAGDQEL LHQAKDFGNY LFNFASAATK KITESVAETA QTIKKSVEEG KIDGIIDKTI IGDFQKEQKK FVEEQHTKKS EAAVPPWVDT NDEETIQQQI LALSADKRNF LRDPPAGVQF NFDFDQMYPV ALVMLQEDEL LSKMRFALVP KLVKEEVFWR NYFYRVSLIK QSAQLTALAA QQQAAGKEEK SNGREQDLPL AEAVRPKTPP VVIKSQLKTQ EDEEEISTSP GVSEFVSDAF DACNLNQEDL RKEMEQLVLD KKQEETAVLE EDSADWEKEL QQELQEYEVV TESEKRDENW DKEIEKMLQE EN
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