About WW domain binding protein VOPP1
WW domain binding protein VOPP1 (VOPP1) is a protein
from Homo sapiens identified by UniProt accession
Q96AW1, 172 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | WW domain binding protein VOPP1 |
|---|
| UniProt accession | Q96AW1 |
|---|
| Gene | VOPP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 172 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (53)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- hepatocellular carcinoma · score 0.06
- appendicular lean mass · score 0.05
- Adie syndrome · score 0.05
- Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
- neoplasm · score 0.04
- Rieger anomaly · score 0.04
- iridocorneal endothelial syndrome · score 0.04
- exfoliation syndrome · score 0.04
- posterior amorphous corneal dystrophy · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96AW1-F1 | alphafold | PREDICTED | 65.59 | — |
Amino-acid sequence (172 residues)
MRRQPAKVAA LLLGLLLECT EAKKHCWYFE GLYPTYYICR SYEDCCGSRC CVRALSIQRL WYFWFLLMMG VLFCCGAGFF IRRRMYPPPL IEEPAFNVSY TRQPPNPGPG AQQPGPPYYT DPGGPGMNPV GNSMAMAFQV PPNSPQGSVA CPPPPAYCNT PPPPYEQVVK AK
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