Protein ARK2N (ARK2N)

Homo sapiens — UniProt Q96B23

Gene: ARK2NHomo sapiensSwissProt reviewed

About Protein ARK2N

Protein ARK2N (ARK2N) is a protein from Homo sapiens identified by UniProt accession Q96B23, 404 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

Target properties

Protein nameProtein ARK2N
UniProt accessionQ96B23
GeneARK2N
OrganismHomo sapiens
Length404 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (54)

Diseases linked to this target (Open Targets).

  • Red cell distribution width · score 0.46
  • mean corpuscular hemoglobin · score 0.45
  • monocyte count · score 0.44
  • neutrophil count · score 0.43
  • mean platelet volume · score 0.43
  • reticulocyte count · score 0.42
  • mean corpuscular volume · score 0.41
  • hemoglobin measurement · score 0.41
  • mean corpuscular hemoglobin concentration · score 0.41
  • leukocyte count · score 0.40

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96B23-F1alphafoldPREDICTED54.12—

Amino-acid sequence (404 residues)

MKMEEAVGKV EELIESEAPP KASEQETAKE EDGSVELESQ VQKDGVADST VISSMPCLLM ELRRDSSESQ LASTESDKPT TGRVYESDSS NHCMLSPSSS GHLADSDTLS SAEENEPSQA ETAVEGDPSG VSGATVGRKS RRSRSESETS TMAAKKNRQS SDKQNGRVAK VKGHRSQKHK ERIRLLRQKR EAAARKKYNL LQDSSTSDSD LTCDSSTSSS DDDEEVSGSS KTITAEIPDG PPVVAHYDMS DTNSDPEVVN VDNLLAAAVV QEHSNSVGGQ DTGATWRTSG LLEELNAEAG HLDPGFLASD KTSAGNAPLN EEINIASSDS EVEIVGVQEH ARCVHPRGGV IQSVSSWKHG SGTQYVSTRQ TQSWTAVTPQ QTWASPAEVV DLTLDEDSRR KYLL

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Quick facts

UniProtQ96B23
GeneARK2N
OrganismHomo sapiens
Length404
Binders0
Diseases54
View on UniProt