Mitochondrial import receptor subunit TOM6 homolog…

About Mitochondrial import receptor subunit TOM6 homolog

Mitochondrial import receptor subunit TOM6 homolog (TOMM6) is a protein from Homo sapiens identified by UniProt accession Q96B49, 74 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	Mitochondrial import receptor subunit TOM6 homolog
UniProt accession	Q96B49
Gene	TOMM6
Organism	Homo sapiens
Length	74 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (33)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.50
mean corpuscular volume · score 0.13
mean corpuscular hemoglobin concentration · score 0.12
erythrocyte count · score 0.12
body mass index · score 0.11
smoking status measurement · score 0.10
mean corpuscular hemoglobin · score 0.10
hip circumference · score 0.08
sleep duration · score 0.08
hemoglobin measurement · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96B49-F1	alphafold	PREDICTED	70.33	—

Amino-acid sequence (74 residues)

MASSTVPVSA AGSANETPEI PDNVGDWLRG VYRFATDRND FRRNLILNLG LFAAGVWLAR NLSDIDLMAP QPGV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Mitochondrial import receptor subunit TOM6 homolog (TOMM6)