About Axin interactor, dorsalization-associated protein
Axin interactor, dorsalization-associated protein (AIDA) is a protein
from Homo sapiens identified by UniProt accession
Q96BJ3, 306 residues long.
MolForge cross-references it against 0 known binders and
49 disease associations.
Target properties
| Protein name | Axin interactor, dorsalization-associated protein |
|---|
| UniProt accession | Q96BJ3 |
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| Gene | AIDA |
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| Organism | Homo sapiens |
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| Length | 306 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (49)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.34
- appendicular lean mass · score 0.26
- coronary artery disease · score 0.24
- myocardial infarction · score 0.19
- heart disease · score 0.12
- Myocardial Ischemia · score 0.11
- body fat percentage · score 0.10
- coronary artery bypass · score 0.10
- angina pectoris · score 0.09
- Vasodilators used in cardiac diseases use measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96BJ3-F1 | alphafold | PREDICTED | 85.77 | — |
Amino-acid sequence (306 residues)
MSEVTRSLLQ RWGASFRRGA DFDSWGQLVE AIDEYQILAR HLQKEAQAQH NNSEFTEEQK KTIGKIATCL ELRSAALQST QSQEEFKLED LKKLEPILKN ILTYNKEFPF DVQPVPLRRI LAPGEEENLE FEEDEEEGGA GAGSPDSFPA RVPGTLLPRL PSEPGMTLLT IRIEKIGLKD AGQCIDPYIT VSVKDLNGID LTPVQDTPVA SRKEDTYVHF NVDIELQKHV EKLTKGAAIF FEFKHYKPKK RFTSTKCFAF MEMDEIKPGP IVIELYKKPT DFKRKKLQLL TKKPLYLHLH QTLHKE
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