Putative uncharacterized protein C3orf49 (C3orf49)

About Putative uncharacterized protein C3orf49

Putative uncharacterized protein C3orf49 (C3orf49) is a protein from Homo sapiens identified by UniProt accession Q96BT1, 292 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Putative uncharacterized protein C3orf49
UniProt accession	Q96BT1
Gene	C3orf49
Organism	Homo sapiens
Length	292 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

leukocyte count · score 0.33
cataract · score 0.30
neutrophil count · score 0.29
schizophrenia · score 0.28
myeloid white cell count · score 0.27
ulcerative colitis · score 0.23
self reported educational attainment · score 0.18
intelligence · score 0.18
monocyte percentage of leukocytes · score 0.16
obsessive-compulsive disorder · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96BT1-F1	alphafold	PREDICTED	60.72	—

Amino-acid sequence (292 residues)

MAQPQLYLPE PFKIAYRKVG QCRRFQQLKK KNGSFKRKGI ERWHRAVSTN LLKQNVLVPK EESSSDSDMG FHESQQNQKS NLKTKVKTAF GRMLSYKYRS KPACASQEGS TDHKEALLSN TQSLLPRIVK EFSSPKLFTA KMRKLSENAT IQLDVVEAET EEITQGNTLL RARRTTKRLS VTSLPSGLQK GPYSPKKRPH FPALKKKKRG MENILRKSDL TVGKLQMQVD DLIETVTDKS MKLLAQRHAE LQQCEFLGDE ILQSSKQFQR ISKRTMRKYK LKNMTTKGPG DS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards