Protein phosphatase 1 regulatory subunit 14B…

About Protein phosphatase 1 regulatory subunit 14B

Protein phosphatase 1 regulatory subunit 14B (PPP1R14B) is a protein from Homo sapiens identified by UniProt accession Q96C90, 147 residues long. MolForge cross-references it against 0 known binders and 82 disease associations.

Target properties

Protein name	Protein phosphatase 1 regulatory subunit 14B
UniProt accession	Q96C90
Gene	PPP1R14B
Organism	Homo sapiens
Length	147 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (82)

Diseases linked to this target (Open Targets).

neoplasm · score 0.10
cancer · score 0.08
triple-negative breast cancer · score 0.08
platelet count · score 0.07
mean corpuscular volume · score 0.07
lung adenocarcinoma · score 0.06
reticulocyte count · score 0.06
Vitiligo · score 0.05
appendicular lean mass · score 0.05
hypertension · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96C90-F1	alphafold	PREDICTED	71.16	—

Amino-acid sequence (147 residues)

MADSGTAGGA ALAAPAPGPG SGGPGPRVYF QSPPGAAGEG PGGADDEGPV RRQGKVTVKY DRKELRKRLN LEEWILEQLT RLYDCQEEEI PELEIDVDEL LDMESDDARA ARVKELLVDC YKPTEAFISG LLDKIRGMQK LSTPQKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Protein phosphatase 1 regulatory subunit 14B (PPP1R14B)