Baculoviral IAP repeat-containing protein 7 (BIRC7)

About Baculoviral IAP repeat-containing protein 7

Baculoviral IAP repeat-containing protein 7 (BIRC7) is a protein from Homo sapiens identified by UniProt accession Q96CA5, 298 residues long. MolForge cross-references it against 0 known binders and 144 disease associations.

Target properties

Protein name	Baculoviral IAP repeat-containing protein 7
UniProt accession	Q96CA5
Gene	BIRC7
Organism	Homo sapiens
Length	298 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (144)

Diseases linked to this target (Open Targets).

neuroticism measurement · score 0.14
neoplasm · score 0.09
melanoma · score 0.09
renal cell carcinoma · score 0.09
hepatocellular carcinoma · score 0.09
osteosarcoma · score 0.07
endometrial carcinoma · score 0.07
colorectal carcinoma · score 0.07
macrothrombocytopenia, isolated, 2, autosomal dominant · score 0.07
thrombocytopenia 4 · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96CA5-F1	alphafold	PREDICTED	71.72	—

Amino-acid sequence (298 residues)

MGPKDSAKCL HRGPQPSHWA AGDGPTQERC GPRSLGSPVL GLDTCRAWDH VDGQILGQLR PLTEEEEEEG AGATLSRGPA FPGMGSEELR LASFYDWPLT AEVPPELLAA AGFFHTGHQD KVRCFFCYGG LQSWKRGDDP WTEHAKWFPS CQFLLRSKGR DFVHSVQETH SQLLGSWDPW EEPEDAAPVA PSVPASGYPE LPTPRREVQS ESAQEPGGVS PAEAQRAWWV LEPPGARDVE AQLRRLQEER TCKVCLDRAV SIVFVPCGHL VCAECAPGLQ LCPICRAPVR SRVRTFLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards