About Ribosome-recycling factor, mitochondrial
Ribosome-recycling factor, mitochondrial (MRRF) is a protein
from Homo sapiens identified by UniProt accession
Q96E11, 262 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Ribosome-recycling factor, mitochondrial |
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| UniProt accession | Q96E11 |
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| Gene | MRRF |
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| Organism | Homo sapiens |
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| Length | 262 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (8)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- myoepithelial tumor · score 0.11
- body mass index · score 0.02
- heel bone mineral density · score 0.02
- pyridoxine-dependent epilepsy caused by ALDH7A1 mutant · score 0.01
- Sepsis · score 0.01
- Parkinson disease · score 0.00
- glioblastoma multiforme · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96E11-F1 | alphafold | PREDICTED | 78.61 | — |
Amino-acid sequence (262 residues)
MALGLKCFRM VHPTFRNYLA ASIRPVSEVT LKTVHERQHG HRQYMAYSAV PVRHFATKKA KAKGKGQSQT RVNINAALVE DIINLEEVNE EMKSVIEALK DNFNKTLNIR TSPGSLDKIA VVTADGKLAL NQISQISMKS PQLILVNMAS FPECTAAAIK AIRESGMNLN PEVEGTLIRV PIPQVTREHR EMLVKLAKQN TNKAKDSLRK VRTNSMNKLK KSKDTVSEDT IRLIEKQISQ MADDTVAELD RHLAVKTKEL LG
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