About RecQ-mediated genome instability protein 2
RecQ-mediated genome instability protein 2 (RMI2) is a protein
from Homo sapiens identified by UniProt accession
Q96E14, 147 residues long.
MolForge cross-references it against 0 known binders and
214 disease associations.
Target properties
| Protein name | RecQ-mediated genome instability protein 2 |
|---|
| UniProt accession | Q96E14 |
|---|
| Gene | RMI2 |
|---|
| Organism | Homo sapiens |
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| Length | 147 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (214)
Diseases linked to this target (Open Targets).
- cancer · score 0.55
- autoinflammatory syndrome with immunodeficiency · score 0.49
- diffuse large B-cell lymphoma · score 0.45
- neoplasm of mature B-cells · score 0.37
- breast ductal adenocarcinoma · score 0.37
- Hodgkins lymphoma · score 0.37
- lymphoid neoplasm · score 0.37
- Endometrial Endometrioid Adenocarcinoma · score 0.37
- lung carcinoma · score 0.37
- Ovarian Endometrioid Adenocarcinoma with Squamous Differentiation · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96E14-F1 | alphafold | PREDICTED | 88.64 | — |
Amino-acid sequence (147 residues)
MAAAADSFSG GPAGVRLPRS PPLKVLAEQL RRDAEGGPGA WRLSRAAAGR GPLDLAAVWM QGRVVMADRG EARLRDPSGD FSVRGLERVP RGRPCLVPGK YVMVMGVVQA CSPEPCLQAV KMTDLSDNPI HESMWELEVE DLHRNIP
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