About Mitochondrial assembly of ribosomal large subunit protein 1
Mitochondrial assembly of ribosomal large subunit protein 1 (MALSU1) is a protein
from Homo sapiens identified by UniProt accession
Q96EH3, 234 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Mitochondrial assembly of ribosomal large subunit protein 1 |
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| UniProt accession | Q96EH3 |
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| Gene | MALSU1 |
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| Organism | Homo sapiens |
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| Length | 234 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (14)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- electrocardiography · score 0.16
- C-reactive protein measurement · score 0.13
- body height · score 0.09
- neoplasm · score 0.05
- transmembrane glycoprotein NMB measurement · score 0.05
- cerebrospinal fluid biomarker measurement · score 0.04
- Parkinson disease · score 0.03
- blood protein measurement · score 0.03
- melanoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96EH3-F1 | alphafold | PREDICTED | 69.22 | — |
Amino-acid sequence (234 residues)
MGPGGRVARL LAPLMWRRAV SSVAGSAVGA EPGLRLLAVQ RLPVGAAFCR ACQTPNFVRG LHSEPGLEER AEGTVNEGRP ESDAADHTGP KFDIDMMVSL LRQENARDIC VIQVPPEMRY TDYFVIVSGT STRHLHAMAF YVVKMYKHLK CKRDPHVKIE GKDTDDWLCV DFGSMVIHLM LPETREIYEL EKLWTLRSYD DQLAQIAPET VPEDFILGIE DDTSSVTPVE LKCE
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