About GTPase IMAP family member 5
GTPase IMAP family member 5 (GIMAP5) is a protein
from Homo sapiens identified by UniProt accession
Q96F15, 307 residues long.
MolForge cross-references it against 0 known binders and
456 disease associations.
Target properties
| Protein name | GTPase IMAP family member 5 |
|---|
| UniProt accession | Q96F15 |
|---|
| Gene | GIMAP5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 307 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (456)
Diseases linked to this target (Open Targets).
- portal hypertension · score 0.57
- Lymphopenia · score 0.19
- lymphopenia · score 0.19
- Immunodeficiency · score 0.18
- Autoimmunity · score 0.18
- liver disease · score 0.18
- sex hormone-binding globulin measurement · score 0.12
- serum albumin measurement · score 0.10
- total blood protein measurement · score 0.10
- Fuchs endothelial corneal dystrophy · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96F15-F1 | alphafold | PREDICTED | 89.36 | — |
Amino-acid sequence (307 residues)
MGGFQRGKYG TMAEGRSEDN LSATPPALRI ILVGKTGCGK SATGNSILGQ PVFESKLRAQ SVTRTCQVKT GTWNGRKVLV VDTPSIFESQ ADTQELYKNI GDCYLLSAPG PHVLLLVIQL GRFTAQDTVA IRKVKEVFGT GAMRHVVILF THKEDLGGQA LDDYVANTDN CSLKDLVREC ERRYCAFNNW GSVEEQRQQQ AELLAVIERL GREREGSFHS NDLFLDAQLL QRTGAGACQE DYRQYQAKVE WQVEKHKQEL RENESNWAYK ALLRVKHLML LHYEIFVFLL LCSILFFIIF LFIFHYI
Explore GTPase IMAP family member 5 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets