About Protein bicaudal D homolog 1
Protein bicaudal D homolog 1 (BICD1) is a protein
from Homo sapiens identified by UniProt accession
Q96G01, 975 residues long.
MolForge cross-references it against 0 known binders and
51 disease associations.
Target properties
| Protein name | Protein bicaudal D homolog 1 |
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| UniProt accession | Q96G01 |
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| Gene | BICD1 |
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| Organism | Homo sapiens |
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| Length | 975 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (51)
Diseases linked to this target (Open Targets).
- DNA methylation · score 0.31
- mean reticulocyte volume · score 0.31
- self reported educational attainment · score 0.21
- hemoglobin A1 measurement · score 0.17
- brain measurement · score 0.16
- thalamus volume · score 0.16
- neuroimaging measurement · score 0.12
- brain volume measurement · score 0.12
- monocyte count · score 0.08
- glioblastoma multiforme · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96G01-F1 | alphafold | PREDICTED | 71.34 | — |
Amino-acid sequence (975 residues)
MAAEEVLQTV DHYKTEIERL TKELTETTHE KIQAAEYGLV VLEEKLTLKQ QYDELEAEYD SLKQELEQLK EAFGQSFSIH RKVAEDGETR EETLLQESAS KEAYYLGKIL EMQNELKQSR AVVTNVQAEN ERLTAVVQDL KENNEMVELQ RIRMKDEIRE YKFREARLLQ DYTELEEENI TLQKLVSTLK QNQVEYEGLK HEIKRFEEET VLLNSQLEDA IRLKEIAEHQ LEEALETLKN EREQKNNLRK ELSQYISLND NHISISVDGL KFAEDGSEPN NDDKMNGHIH GPLVKLNGDY RTPTLRKGES LNPVSDLFSE LNISEIQKLK QQLMQVEREK AILLANLQES QTQLEHTKGA LTEQHERVHR LTEHVNAMRG LQSSKELKAE LDGEKGRDSG EEAHDYEVDI NGLEILECKY RVAVTEVIDL KAEIKALKEK YNKSVENYTD EKAKYESKIQ MYDEQVTSLE KTTKESGEKM AHMEKELQKM TSIANENHST LNTAQDELVT FSEELAQLYH HVCLCNNETP NRVMLDYYRQ SRVTRSGSLK GPDDPRGLLS PRLARRGVSS PVETRTSSEP VAKESTEASK EPSPTKTPTI SPVITAPPSS PVLDTSDIRK EPMNIYNLNA IIRDQIKHLQ KAVDRSLQLS RQRAAARELA PMIDKDKEAL MEEILKLKSL LSTKREQIAT LRAVLKANKQ TAEVALANLK NKYENEKAMV TETMTKLRNE LKALKEDAAT FSSLRAMFAT RCDEYVTQLD EMQRQLAAAE DEKKTLNTLL RMAIQQKLAL TQRLEDLEFD HEQSRRSKGK LGKSKIGSPK VSGEASVTVP TIDTYLLHSQ GPQTPNIRVS SGTQRKRQFS PSLCDQSRPR TSGASYLQNL LRVPPDPTST ESFLLKGPPS MSEFIQGHRL SKEKRLTVAP PDCQQPAASV PPQCSQLAGR QDCPTVSPDT ALPEEQPHSS SQCAPLHCLS KPPHP
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