Cilia- and flagella-associated protein 36 (CFAP36)

About Cilia- and flagella-associated protein 36

Cilia- and flagella-associated protein 36 (CFAP36) is a protein from Homo sapiens identified by UniProt accession Q96G28, 342 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	Cilia- and flagella-associated protein 36
UniProt accession	Q96G28
Gene	CFAP36
Organism	Homo sapiens
Length	342 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

systolic blood pressure · score 0.31
cortical thickness · score 0.12
body height · score 0.11
hypothyroidism · score 0.08
Antiglaucoma preparations and miotics use measurement · score 0.07
metabolite measurement · score 0.07
isolated asymptomatic elevation of creatine phosphokinase · score 0.07
autoimmune thyroid disease · score 0.06
Vitiligo · score 0.06
Thyroid preparation use measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96G28-F1	alphafold	PREDICTED	73.00	—

Amino-acid sequence (342 residues)

MAAEEEDEVE WVVESIAGFL RGPDWSIPIL DFVEQKCEVF DDEEESKLTY TEIHQEYKEL VEKLLEGYLK EIGINEDQFQ EACTSPLAKT HTSQAILQPV LAAEDFTIFK AMMVQKNIEM QLQAIRIIQE RNGVLPDCLT DGSDVVSDLE HEEMKILREV LRKSKEEYDQ EEERKRKKQL SEAKTEEPTV HSSEAAIMNN SQGDGEHFAH PPSEVKMHFA NQSIEPLGRK VERSETSSLP QKDLKIPGLE HASIEGPIAN LSVLGTEELR QREHYLKQKR DKLMSMRKDM RTKQIQNMEQ KGKPTGEVEE MTEKPEMTAE EKQTLLKRRL LAEKLKEEVI NK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards