Calmodulin-like protein 4 (CALML4)

About Calmodulin-like protein 4

Calmodulin-like protein 4 (CALML4) is a protein from Homo sapiens identified by UniProt accession Q96GE6, 196 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Calmodulin-like protein 4
UniProt accession	Q96GE6
Gene	CALML4
Organism	Homo sapiens
Length	196 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

eosinophil count · score 0.33
eosinophil percentage of leukocytes · score 0.19
diastolic blood pressure · score 0.12
hemoglobin measurement · score 0.05
lymphocyte count · score 0.04
Pelvic Inflammatory Disease · score 0.03
platelet crit · score 0.03
IGF-1 measurement · score 0.02
hematocrit · score 0.02
gonorrhea · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96GE6-F1	alphafold	PREDICTED	75.67	—

Amino-acid sequence (196 residues)

MAAEHLLPGP PPSLADFRLE AGGKGTERGS GSSKPTGSSR GPRMAKFLSQ DQINEYKECF SLYDKQQRGK IKATDLMVAM RCLGASPTPG EVQRHLQTHG IDGNGELDFS TFLTIMHMQI KQEDPKKEIL LAMLMVDKEK KGYVMASDLR SKLTSLGEKL THKEVDDLFR EADIEPNGKV KYDEFIHKIT LPGRDY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards