Distal membrane-arm assembly complex protein 1 (DMAC1)

About Distal membrane-arm assembly complex protein 1

Distal membrane-arm assembly complex protein 1 (DMAC1) is a protein from Homo sapiens identified by UniProt accession Q96GE9, 116 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Distal membrane-arm assembly complex protein 1
UniProt accession	Q96GE9
Gene	DMAC1
Organism	Homo sapiens
Length	116 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

protein measurement · score 0.29
pulse pressure measurement · score 0.25
systolic blood pressure · score 0.25
vital capacity · score 0.23
gut microbiome measurement · score 0.21
metabolite measurement · score 0.19
chronotype measurement · score 0.17
refractive error measurement · score 0.13
visual perception measurement · score 0.09
neoplasm · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96GE9-F1	alphafold	PREDICTED	59.55	—

Amino-acid sequence (116 residues)

MGSRLSQPFE SYITAPPGTA AAPAKPAPPA TPGAPTSPAE HRLLKTCWSC RVLSGLGLMG AGGYVYWVAR KPMKMGYPPS PWTITQMVIG LSENQGIATW GIVVMADPKG KAYRVV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards