X antigen family member 2 (XAGE2)

About X antigen family member 2

X antigen family member 2 (XAGE2) is a protein from Homo sapiens identified by UniProt accession Q96GT9, 111 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	X antigen family member 2
UniProt accession	Q96GT9
Gene	XAGE2
Organism	Homo sapiens
Length	111 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

fibromyalgia · score 0.02
triple-negative breast cancer · score 0.00
lung adenocarcinoma · score 0.00
carcinosarcoma · score 0.00
Ewing sarcoma · score 0.00
cancer · score 0.00
rhabdomyosarcoma · score 0.00
neoplasm · score 0.00
metastatic melanoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96GT9-F1	alphafold	PREDICTED	64.33	—

Amino-acid sequence (111 residues)

MSWRGRSTYR PRPRRSLQPP ELIGAMLEPT DEEPKEEKPP TKSRNPTPDQ KREDDQGAAE IQVPDLEADL QELCQTKTGD GCEGGTDVKG KILPKAEHFK MPEAGEGKSQ V

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards