Zinc transporter ZIP13 (SLC39A13)

About Zinc transporter ZIP13

Zinc transporter ZIP13 (SLC39A13) is a protein from Homo sapiens identified by UniProt accession Q96H72, 371 residues long. MolForge cross-references it against 0 known binders and 488 disease associations.

Target properties

Protein name	Zinc transporter ZIP13
UniProt accession	Q96H72
Gene	SLC39A13
Organism	Homo sapiens
Length	371 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (488)

Diseases linked to this target (Open Targets).

Ehlers-Danlos syndrome, spondylocheirodysplastic type · score 0.75
Spondyloepimetaphyseal dysplasia - abnormal dentition · score 0.46
spondyloepimetaphyseal dysplasia-abnormal dentition syndrome · score 0.46
platelet count · score 0.35
creatinine measurement · score 0.30
cystatin C measurement · score 0.26
platelet crit · score 0.25
glomerular filtration rate · score 0.24
mean platelet volume · score 0.23
IGF-1 measurement · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96H72-F1	alphafold	PREDICTED	75.32	—

Amino-acid sequence (371 residues)

MPGCPCPGCG MAGPRLLFLT ALALELLERA GGSQPALRSR GTATACRLDN KESESWGALL SGERLDTWIC SLLGSLMVGL SGVFPLLVIP LEMGTMLRSE AGAWRLKQLL SFALGGLLGN VFLHLLPEAW AYTCSASPGG EGQSLQQQQQ LGLWVIAGIL TFLALEKMFL DSKEEGTSQA PNKDPTAAAA ALNGGHCLAQ PAAEPGLGAV VRSIKVSGYL NLLANTIDNF THGLAVAASF LVSKKIGLLT TMAILLHEIP HEVGDFAILL RAGFDRWSAA KLQLSTALGG LLGAGFAICT QSPKGVVGCS PAAEETAAWV LPFTSGGFLY IALVNVLPDL LEEEDPWRSL QQLLLLCAGI VVMVLFSLFV D

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards