About Peroxisomal membrane protein 11C
Peroxisomal membrane protein 11C (PEX11G) is a protein
from Homo sapiens identified by UniProt accession
Q96HA9, 241 residues long.
MolForge cross-references it against 0 known binders and
15 disease associations.
Target properties
| Protein name | Peroxisomal membrane protein 11C |
|---|
| UniProt accession | Q96HA9 |
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| Gene | PEX11G |
|---|
| Organism | Homo sapiens |
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| Length | 241 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (15)
Diseases linked to this target (Open Targets).
- opioid overdose severity measurement · score 0.04
- cystatin C measurement · score 0.04
- serum urea measurement · score 0.04
- diastolic blood pressure · score 0.03
- hypertension · score 0.02
- cardiovascular disease · score 0.02
- hepatocellular carcinoma · score 0.02
- COVID-19 · score 0.01
- Sepsis · score 0.01
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96HA9-F1 | alphafold | PREDICTED | 91.84 | — |
Amino-acid sequence (241 residues)
MASLSGLASA LESYRGRDRL IRVLGYCCQL VGGVLVEQCP ARSEVGTRLL VVSTQLSHCR TILRLFDDLA MFVYTKQYGL GAQEEDAFVR CVSVLGNLAD QLYYPCEHVA WAADARVLHV DSSRWWTLST TLWALSLLLG VARSLWMLLK LRQRLRSPTA PFTSPLPRGK RRAMEAQMQS EALSLLSNLA DLANAVHWLP RGVLWAGRFP PWLVGLMGTI SSILSMYQAA RAGGQAEATT P
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