Protein preY, mitochondrial (PYURF)

About Protein preY, mitochondrial

Protein preY, mitochondrial (PYURF) is a protein from Homo sapiens identified by UniProt accession Q96I23, 114 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Protein preY, mitochondrial
UniProt accession	Q96I23
Gene	PYURF
Organism	Homo sapiens
Length	114 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.55
hyperphosphatasia-intellectual disability syndrome · score 0.44
lysosomal storage disease · score 0.37
mitochondrial disease · score 0.33
urate measurement · score 0.15
handedness · score 0.03
mean platelet volume · score 0.02
FEV/FVC ratio · score 0.02
alkaline phosphatase measurement · score 0.02
renal system measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96I23-F1	alphafold	PREDICTED	76.80	—

Amino-acid sequence (114 residues)

MLSGARCRLA SALRGTRAPP SAVARRCLHA SGSRPLADRG KKTEEPPRDF DPALLEFLVC PLSKKPLRYE ASTNELINEE LGIAYPIIDG IPNMIPQAAR MTRQSKKQEE VEQR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards