About Far upstream element-binding protein 3
Far upstream element-binding protein 3 (FUBP3) is a protein
from Homo sapiens identified by UniProt accession
Q96I24, 572 residues long.
MolForge cross-references it against 0 known binders and
50 disease associations.
Target properties
| Protein name | Far upstream element-binding protein 3 |
| UniProt accession | Q96I24 |
| Gene | FUBP3 |
| Organism | Homo sapiens |
| Length | 572 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- body height · score 0.37
- heel bone mineral density · score 0.34
- body weights and measures · score 0.32
- alkaline phosphatase measurement · score 0.28
- femoral neck bone mineral density · score 0.25
- bone quantitative ultrasound measurement · score 0.23
- cystatin C measurement · score 0.23
- PHF-tau measurement · score 0.23
- bone density · score 0.22
- sitting height measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q96I24-F1 | alphafold | PREDICTED | 65.83 | — |
Amino-acid sequence (572 residues)
MAELVQGQSA PVGMKAEGFV DALHRVRQIA AKIDSIPHLN NSTPLVDPSV YGYGVQKRPL DDGVGNQLGA LVHQRTVITE EFKVPDKMVG FIIGRGGEQI SRIQAESGCK IQIASESSGI PERPCVLTGT PESIEQAKRL LGQIVDRCRN GPGFHNDIDS NSTIQEILIP ASKVGLVIGR GGETIKQLQE RTGVKMVMIQ DGPLPTGADK PLRITGDAFK VQQAREMVLE IIREKDQADF RGVRGDFNSR MGGGSIEVSV PRFAVGIVIG RNGEMIKKIQ NDAGVRIQFK PDDGISPERA AQVMGPPDRC QHAAHIISEL ILTAQERDGF GGLAAARGRG RGRGDWSVGA PGGVQEITYT VPADKCGLVI GKGGENIKSI NQQSGAHVEL QRNPPPNSDP NLRRFTIRGV PQQIEVARQL IDEKVGGTNL GAPGAFGQSP FSQPPAPPHQ NTFPPRSSGC FPNMAAKVNG NPHSTPVSGP PAFLTQGWGS TYQAWQQPTQ QVPSQQSQPQ SSQPNYSKAW EDYYKKQSHA ASAAPQASSP PDYTMAWAEY YRQQVAFYGQ TLGQAQAHSQ EQ
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