About Transmembrane protein 101
Transmembrane protein 101 (TMEM101) is a protein
from Homo sapiens identified by UniProt accession
Q96IK0, 257 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Transmembrane protein 101 |
|---|
| UniProt accession | Q96IK0 |
|---|
| Gene | TMEM101 |
|---|
| Organism | Homo sapiens |
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| Length | 257 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- blood phosphate measurement · score 0.19
- sex hormone-binding globulin measurement · score 0.07
- sitting height measurement · score 0.06
- pulse pressure measurement · score 0.05
- body height · score 0.04
- heel bone mineral density · score 0.04
- apolipoprotein B measurement · score 0.03
- erythrocyte count · score 0.03
- leukocyte count · score 0.02
- Kidney Oncocytoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96IK0-F1 | alphafold | PREDICTED | 89.43 | — |
Amino-acid sequence (257 residues)
MASKIGSRRW MLQLIMQLGS VLLTRCPFWG CFSQLMLYAE RAEARRKPDI PVPYLYFDMG AAVLCASFMS FGVKRRWFAL GAALQLAIST YAAYIGGYVH YGDWLKVRMY SRTVAIIGGF LVLASGAGEL YRRKPRSRSL QSTGQVFLGI YLICVAYSLQ HSKEDRLAYL NHLPGGELMI QLFFVLYGIL ALAFLSGYYV TLAAQILAVL LPPVMLLIDG NVAYWHNTRR VEFWNQMKLL GESVGIFGTA VILATDG
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