Putative protein-lysine deacylase ABHD14B (ABHD14B)

About Putative protein-lysine deacylase ABHD14B

Putative protein-lysine deacylase ABHD14B (ABHD14B) is a protein from Homo sapiens identified by UniProt accession Q96IU4, 210 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Putative protein-lysine deacylase ABHD14B
UniProt accession	Q96IU4
Gene	ABHD14B
Organism	Homo sapiens
Length	210 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

reticulocyte count · score 0.15
age at first birth measurement · score 0.07
body height · score 0.06
self reported educational attainment · score 0.03
Immature Reticulocyte Fraction Measurement · score 0.03
low density lipoprotein cholesterol measurement · score 0.02
erythrocyte count · score 0.02
neoplasm · score 0.01
non-proliferative diabetic retinopathy · score 0.01
chronic kidney disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96IU4-F1	alphafold	PREDICTED	96.91	—

Amino-acid sequence (210 residues)

MAASVEQREG TIQVQGQALF FREALPGSGQ ARFSVLLLHG IRFSSETWQN LGTLHRLAQA GYRAVAIDLP GLGHSKEAAA PAPIGELAPG SFLAAVVDAL ELGPPVVISP SLSGMYSLPF LTAPGSQLPG FVPVAPICTD KINAANYASV KTPALIVYGD QDPMGQTSFE HLKQLPNHRV LIMKGAGHPC YLDKPEEWHT GLLDFLQGLQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards