About Androgen-dependent TFPI-regulating protein
Androgen-dependent TFPI-regulating protein (ADTRP) is a protein
from Homo sapiens identified by UniProt accession
Q96IZ2, 230 residues long.
MolForge cross-references it against 0 known binders and
74 disease associations.
Target properties
| Protein name | Androgen-dependent TFPI-regulating protein |
|---|
| UniProt accession | Q96IZ2 |
|---|
| Gene | ADTRP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 230 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (74)
Diseases linked to this target (Open Targets).
- wellbeing measurement · score 0.49
- lymphocyte count · score 0.47
- neuroticism measurement · score 0.46
- leukocyte count · score 0.41
- depressive symptom measurement · score 0.40
- low density lipoprotein cholesterol measurement · score 0.37
- Abnormality of refraction · score 0.34
- cleft lip · score 0.33
- alcohol consumption measurement · score 0.33
- eosinophil count · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96IZ2-F1 | alphafold | PREDICTED | 90.95 | — |
Amino-acid sequence (230 residues)
MTKTSTCIYH FLVLSWYTFL NYYISQEGKD EVKPKILANG ARWKYMTLLN LLLQTIFYGV TCLDDVLKRT KGGKDIKFLT AFRDLLFTTL AFPVSTFVFL AFWILFLYNR DLIYPKVLDT VIPVWLNHAM HTFIFPITLA EVVLRPHSYP SKKTGLTLLA AASIAYISRI LWLYFETGTW VYPVFAKLSL LGLAAFFSLS YVFIASIYLL GEKLNHWKWG DMRQPRKKRK
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