Small nuclear protein PRAC1 (PRAC1)

About Small nuclear protein PRAC1

Small nuclear protein PRAC1 (PRAC1) is a protein from Homo sapiens identified by UniProt accession Q96KF2, 57 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	Small nuclear protein PRAC1
UniProt accession	Q96KF2
Gene	PRAC1
Organism	Homo sapiens
Length	57 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

appendicular lean mass · score 0.21
restless legs syndrome · score 0.19
prostate carcinoma · score 0.17
balding measurement · score 0.16
total cholesterol measurement · score 0.15
low density lipoprotein cholesterol measurement · score 0.13
systolic blood pressure · score 0.09
eosinophil percentage of leukocytes · score 0.04
infection · score 0.03
infect · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96KF2-F1	alphafold	PREDICTED	59.37	—

Amino-acid sequence (57 residues)

MLCAHFSDQG PAHLTTSKSA FLSNKKTSTL KHLLGETRSD GSACNSGISG GRGRKIP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards