About RNA-binding region-containing protein 3
RNA-binding region-containing protein 3 (RNPC3) is a protein
from Homo sapiens identified by UniProt accession
Q96LT9, 517 residues long.
MolForge cross-references it against 0 known binders and
332 disease associations.
Target properties
| Protein name | RNA-binding region-containing protein 3 |
|---|
| UniProt accession | Q96LT9 |
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| Gene | RNPC3 |
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| Organism | Homo sapiens |
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| Length | 517 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (332)
Diseases linked to this target (Open Targets).
- isolated growth hormone deficiency type IB · score 0.62
- neurodegenerative disease · score 0.53
- pituitary hormone deficiency, combined or isolated, 8 · score 0.51
- Decreased response to growth hormone stimulation test · score 0.45
- isolated growth hormone deficiency type IA · score 0.37
- blood protein measurement · score 0.24
- chronic lymphocytic leukemia · score 0.23
- genetic disorder · score 0.19
- Malignant Urinary System Neoplasm · score 0.14
- neoplasm · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96LT9-F1 | alphafold | PREDICTED | 67.40 | — |
Amino-acid sequence (517 residues)
MAAPEQPLAI SRGCTSSSSL SPPRGDRTLL VRHLPAELTA EEKEDLLKYF GAQSVRVLSD KGRLKHTAFA TFPNEKAAIK ALTRLHQLKL LGHTLVVEFA KEQDRVHSPC PTSGSEKKKR SDDPVEDDKE KKELGYLTVE NGIAPNHGLT FPLNSCLKYM YPPPSSTILA NIVNALASVP KFYVQVLHLM NKMNLPTPFG PITARPPMYE DYMPLHAPLP PTSPQPPEEP PLPDEDEELS SEESEYESTD DEDRQRMNKL MELANLQPKR PKTIKQRHVR KKRKIKDMLN TPLCPSHSSL HPVLLPSDVF DQPQPVGNKR IEFHISTDMP AAFKKDLEKE QNCEEKNHDL PATEVDASNI GFGKIFPKPN LDITEEIKED SDEMPSECIS RRELEKGRIS REEMETLSVF RSYEPGEPNC RIYVKNLAKH VQEKDLKYIF GRYVDFSSET QRIMFDIRLM KEGRMKGQAF IGLPNEKAAA KALKEANGYV LFGKPMVVQF ARSARPKQDP KEGKRKC
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