About Caspase recruitment domain-containing protein 19
Caspase recruitment domain-containing protein 19 (CARD19) is a protein
from Homo sapiens identified by UniProt accession
Q96LW7, 228 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Caspase recruitment domain-containing protein 19 |
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| UniProt accession | Q96LW7 |
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| Gene | CARD19 |
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| Organism | Homo sapiens |
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| Length | 228 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (41)
Diseases linked to this target (Open Targets).
- adolescent idiopathic scoliosis · score 0.24
- mean platelet volume · score 0.17
- serum alanine aminotransferase measurement · score 0.09
- C1 inhibitor deficiency · score 0.07
- autoimmune disease · score 0.07
- emotional symptom measurement · score 0.06
- Hashimoto's thyroiditis · score 0.06
- aspartate aminotransferase measurement · score 0.06
- pemphigus vulgaris · score 0.05
- blood protein measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96LW7-F1 | alphafold | PREDICTED | 63.13 | — |
Amino-acid sequence (228 residues)
MTDQTYCDRL VQDTPFLTGH GRLSEQQVDR IILQLNRYYP QILTNKEAEK FRNPKASLRV RLCDLLSHLQ RSGERDCQEF YRALYIHAQP LHSRLPSRHA LRKFHITNHA CLVLARGGHP SLPLMAWMSS MTTQVCCSPG LASPLASAPP QRPPSGPEGR VWQAQAVQML VSVSHFLPLP PSLSHGSFHT AWGILYVHSC PSFSNLIPRG SLHVCVDSNL VPTAAWRS
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