Zinc finger protein 597 (ZNF597)

About Zinc finger protein 597

Zinc finger protein 597 (ZNF597) is a protein from Homo sapiens identified by UniProt accession Q96LX8, 424 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.

Target properties

Protein name	Zinc finger protein 597
UniProt accession	Q96LX8
Gene	ZNF597
Organism	Homo sapiens
Length	424 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (71)

Diseases linked to this target (Open Targets).

insulin like growth factor measurement · score 0.23
body height · score 0.13
IGF-1 measurement · score 0.06
Familial ocular anterior segment mesenchymal dysgenesis · score 0.06
eosinophil count · score 0.06
X-linked intellectual disability-retinitis pigmentosa syndrome · score 0.05
Peters anomaly · score 0.05
iridocorneal endothelial syndrome · score 0.05
Rieger anomaly · score 0.05
spinocerebellar ataxia type 17 · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96LX8-F1	alphafold	PREDICTED	48.76	—

Amino-acid sequence (424 residues)

MASMPPTPEA QGPILFEDLA VYFSQEECVT LHPAQRSLSK DGTKESLEDA ALMGEEGKPE INQQLSLESM ELDELALEKY PIAAPLVPYP EKSSEDGVGN PEAKILSGTP TYKRRVISLL VTIENHTPLV ELSEYLGTNT LSEILDSPWE GAKNVYKCPE CDQNFSDHSY LVLHQKIHSG EKKHKCGDCG KIFNHRANLR THRRIHTGEK PYKCAKCSAS FRQHSHLSRH MNSHVKEKPY TCSICGRGFM WLPGLAQHQK SHSAENTYES TNCDKHFNEK PNLALPEETF VSGPQYQHTK CMKSFRQSLY PALSEKSHDE DSERCSDDGD NFFSFSKFKP LQCPDCDMTF PCFSELISHQ NIHTEERPHK CKTCEESFAL DSELACHQKS HMLAEPFKCT VCGKTFKSNL HLITHKRTHI KNTT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards