About Zinc finger protein 560
Zinc finger protein 560 (ZNF560) is a protein
from Homo sapiens identified by UniProt accession
Q96MR9, 790 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Zinc finger protein 560 |
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| UniProt accession | Q96MR9 |
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| Gene | ZNF560 |
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| Organism | Homo sapiens |
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| Length | 790 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (18)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- Familial prostate cancer · score 0.11
- prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- Down syndrome · score 0.06
- appendicular lean mass · score 0.05
- papillary thyroid carcinoma · score 0.04
- serum gamma-glutamyl transferase measurement · score 0.03
- lung adenocarcinoma · score 0.03
- laryngeal squamous cell carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96MR9-F1 | alphafold | PREDICTED | 64.17 | — |
Amino-acid sequence (790 residues)
MAYCLTNCYQ YSVTFEDTAV DFTQEEWILL DPVQRNLYRD VMLENYENVA KVGFQLFKPS VISWLEEEEL RTLQQGVLQD WAIKHQTSVS ALQQEFWKIQ TSNGIQMDLV TFDSVAVEFT QEEWTLLDPA QRNLYSDVML ENYKNLSSVG YQLFKPSLIS WLEEEEELST LPRVLQEWKM CLKTKGPALW QDNFCLKTLN GIQLARNQNG EELYDCKQCE DVFCKHPCLK TNMSTQNRGN TSECIQYAKD LLSLYNKTST IRKVSVFSKH GKSFRLILNV QVQRKCTQDK SFEGTDYGKA FIYQSYLEAH RKTQSGEKLN EWKQCGEAFT HSTSHAVNVE THIIKNPYEC KECGKDFRYP THLNNHMQTH IGIKPYKCKH CGKTFTVPSG FLEHVRTHTG EKPYGCKECG KAFGTSAGLI EHIRCHAREK TFKCDHCGKA FISYPSLFGH LRVHNGEKPY EHKEYGKAFG TSSGVIEDRR SNTGQKRFDC DQCGKVFVSF SSLFAHLRTH TGEKPFKCYK CGKPFTSSAC LRIHMRTHTE ERLYQCKKCG KAFTKCSYLT KHLRTHAGEK PYECMKCGKA FTERSYLTKH LRRHSGEKPY ECKKCGKAFT ERSDLTKHLR RHTGDKPYEY KDCGKAFVVS SSLVDHLRTH TGYKPYKCNA CEKAYSRSCV LTQHLKTHAA EKTSECNACG NSFRNSMCFH DRLKTLTKIK PYKCKDCGKA FTCHSDLTNH VRIHTGEKPY KCKECGKAFR TSSGRIQHLR THMGEKPFEC DQCGKAFASF SARIAHLKTH
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