About Coiled-coil domain-containing protein 43
Coiled-coil domain-containing protein 43 (CCDC43) is a protein
from Homo sapiens identified by UniProt accession
Q96MW1, 224 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein 43 |
|---|
| UniProt accession | Q96MW1 |
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| Gene | CCDC43 |
|---|
| Organism | Homo sapiens |
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| Length | 224 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (14)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.08
- body height · score 0.05
- gonorrhea · score 0.04
- oral squamous cell carcinoma · score 0.04
- platelet component distribution width · score 0.04
- pulse pressure measurement · score 0.03
- cognitive function measurement · score 0.03
- neoplasm · score 0.02
- platelet crit · score 0.02
- lymph node metastatic carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96MW1-F1 | alphafold | PREDICTED | 76.04 | — |
Amino-acid sequence (224 residues)
MAAPSEVAAI APGEGDGGGG GFGSWLDGRL EALGVDRAVY GAYILGILQE EEEEEKLDAL QGILSAFLEE DSLLNICKEI VERWSETQNV VTKVKKEDEV QAIATLIEKQ AQIVVKPRMV SEEEKQRKAA LLAQYADVTD EEDEADEKDD SGATTMNIGS DKLLFRNTNV EDVLNARKLE RDSLRDESQR KKEQDKLQRE RDKLAKQERK EKEKKRTQRG ERKR
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