Zinc finger protein 48 (ZNF48)

About Zinc finger protein 48

Zinc finger protein 48 (ZNF48) is a protein from Homo sapiens identified by UniProt accession Q96MX3, 618 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Zinc finger protein 48
UniProt accession	Q96MX3
Gene	ZNF48
Organism	Homo sapiens
Length	618 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.44
prostate carcinoma · score 0.11
prostate cancer · score 0.11
Familial prostate cancer · score 0.11
blood protein measurement · score 0.03
cardiac troponin I measurement · score 0.02
Myopia · score 0.00
myopia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96MX3-F1	alphafold	PREDICTED	62.36	—

Amino-acid sequence (618 residues)

MERAVEPWGP DLHRPEEREP QRGARTGLGS ENVISQPNEF EHTPQEDDLG FKEEDLAPDH EVGNASLKPE GIQNWDDLWV QREGLGKPQP RDRGPRLLGE PRWGQASSDR AAVCGECGKS FRQMSDLVKH QRTHTGEKPY KCGVCGKGFG DSSARIKHQR THSGEKPYRA RPPAQGPPKI PRSRIPAGER PTICGECGKS FRQSSDLVKH QRTHTGEKPY KCGICGKGFG DSSARIKHQR THRGEQPPRP VVPRRQPSRA ATAATQGPKA QDKPYICTDC GKRFVLSCSL LSHQRSHLGP KPFGCDVCGK EFARGSDLVK HLRVHTGEKP YLCPECGKGF ADSSARVKHL RTHSGERPHA CPECDRTFSL SSTLLRHRLT HMEPQDFSFP GYPLPALIPS PPPPPLGTSP PLTPRSPSHS GEPFGLPGLE PEPGGPQAGE PPPPLAGDKP HKCPECGKGF RRSSDLVKHH RVHTGEKPYL CPECGKGFAD SSARVKHLRT HRGERARPPP PSTLLRPHNP PGPVPMAPRP RVRAQPSGPS QPHVCGFCGK EFPRSSDLVK HRRTHTGEKP YKCAECGKGF GDSSARIKHQ RGHLVLTPFG IGDGRARPLK QEAATGLE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards