Nucleolar protein 4-like (NOL4L)

About Nucleolar protein 4-like

Nucleolar protein 4-like (NOL4L) is a protein from Homo sapiens identified by UniProt accession Q96MY1, 436 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.

Target properties

Protein name	Nucleolar protein 4-like
UniProt accession	Q96MY1
Gene	NOL4L
Organism	Homo sapiens
Length	436 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (71)

Diseases linked to this target (Open Targets).

Red cell distribution width · score 0.44
smoking status measurement · score 0.39
monocyte count · score 0.37
smoking initiation · score 0.37
mean platelet volume · score 0.37
insomnia measurement · score 0.36
erythrocyte count · score 0.36
mean corpuscular hemoglobin · score 0.35
reticulocyte count · score 0.35
eosinophil count · score 0.35

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96MY1-F1	alphafold	PREDICTED	61.16	—

Amino-acid sequence (436 residues)

MSDSTWMSAD PHLASSLSPS QDERMRSPQN LHSQEDDDSS SESGSGNGSS TLNPSTSSST QGDPAFPEMN GNGAVAPMDF TTAAEDQPIN LCDKLPPATA LGTASYPSDG CGADGLRSRV KYGVKTTPES PPYSSGSYDS IKTEVSGCPE DLTVGRAPTA DDDDDDHDDH EDNDKMNDSE GMDPERLKAF NMFVRLFVDE NLDRMVPISK QPKEKIQAII ESCSRQFPEF QERARKRIRT YLKSCRRMKK NGMEMTRPTP PHLTSAMAEN ILAAACESET RKAAKRMRLE IYQSSQDEPI ALDKQHSRDS AAITHSTYSL PASSYSQDPV YANGGLNYSY RGYGALSSNL QPPASLQTGN HSNGPTDLSM KGGASTTSTT PTPTPSSTST SRPVPTAQLS PTEISAVRQL IAGYRESAAF LLRSADELEN LILQQN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards