Spermatogenesis-associated protein 33 (SPATA33)

About Spermatogenesis-associated protein 33

Spermatogenesis-associated protein 33 (SPATA33) is a protein from Homo sapiens identified by UniProt accession Q96N06, 139 residues long. MolForge cross-references it against 0 known binders and 143 disease associations.

Target properties

Protein name	Spermatogenesis-associated protein 33
UniProt accession	Q96N06
Gene	SPATA33
Organism	Homo sapiens
Length	139 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (143)

Diseases linked to this target (Open Targets).

skin pigmentation measurement · score 0.50
hair colour measurement · score 0.49
skin pigmentation · score 0.41
melanoma · score 0.26
basal cell carcinoma · score 0.23
BMI-adjusted hip circumference · score 0.23
hemoglobin measurement · score 0.23
neurodegenerative disease · score 0.21
BMI-adjusted waist circumference · score 0.21
glomerular filtration rate · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96N06-F1	alphafold	PREDICTED	65.82	—

Amino-acid sequence (139 residues)

MVTHAAGART FCEEQKKGST YSVPKSKEKL MEKHSQEARQ ADRESEKPVD SLHPGAGTAK HPPPAASLEE KPDVKQKSSR KKVVVPQIII TRASNETLVS CSSSGSDQQR TIREPEDWGP YRRHRNPSTA DAYNSHLKE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards