Zinc finger protein 396 (ZNF396)

About Zinc finger protein 396

Zinc finger protein 396 (ZNF396) is a protein from Homo sapiens identified by UniProt accession Q96N95, 335 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Zinc finger protein 396
UniProt accession	Q96N95
Gene	ZNF396
Organism	Homo sapiens
Length	335 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

wellbeing measurement · score 0.36
mathematical ability · score 0.32
creatinine measurement · score 0.25
neuroticism measurement · score 0.17
depressive symptom measurement · score 0.17
appendicular lean mass · score 0.04
protein measurement · score 0.04
body height · score 0.03
adolescent idiopathic scoliosis · score 0.03
eosinophilic esophagitis · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96N95-F1	alphafold	PREDICTED	57.15	—

Amino-acid sequence (335 residues)

MSAKLGKSSS LLTQTSEECN GILTEKMEEE EQTCDPDSSL HWSSSYSPET FRQQFRQFGY QDSPGPHEAL SRLWELCHLW LRPEVHTKEQ ILELLVLEQF LAILPKELQA WVQKHHPENG EETVTMLEDV ERELDGPKQI FFGRRKDMIA EKLAPSEITE ELPSSQLMPV KKQLQGASWE LQSLRPHDED IKTTNVKSAS RQKTSLGIEL HCNVSNILHM NGSQSSTYRG TYEQDGRFEK RQGNPSWKKQ QKCDECGKIF SQSSALILHQ RIHSGKKPYA CDECAKAFSR SAILIQHRRT HTGEKPYKCH DCGKAFSQSS NLFRHRKRHI RKKVP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards