Rab-interacting lysosomal protein (RILP)

About Rab-interacting lysosomal protein

Rab-interacting lysosomal protein (RILP) is a protein from Homo sapiens identified by UniProt accession Q96NA2, 401 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	Rab-interacting lysosomal protein
UniProt accession	Q96NA2
Gene	RILP
Organism	Homo sapiens
Length	401 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.32
Ischemic stroke · score 0.09
neoplasm · score 0.04
reticulocyte count · score 0.04
mean platelet volume · score 0.03
platelet crit · score 0.03
blood protein measurement · score 0.03
HbA1c measurement · score 0.02
reticulocyte measurement · score 0.02
brain aneurysm · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96NA2-F1	alphafold	PREDICTED	69.90	—

Amino-acid sequence (401 residues)

MEPRRAAPGV PGWGSREAAG SASAAELVYH LAGALGTELQ DLARRFGPEA AAGLVPLVVR ALELLEQAAV GPAPDSLQVS AQPAEQELRR LREENERLRR ELRAGPQEER ALLRQLKEVT DRQRDELRAH NRDLRQRGQE TEALQEQLQR LLLVNAELRH KLAAMQTQLR AAQDRERERQ QPGEAATPQA KERARGQAGR PGHQHGQEPE WATAGAGAPG NPEDPAEAAQ QLGRPSEAGQ CRFSREEFEQ ILQERNELKA KVFLLKEELA YFQRELLTDH RVPGLLLEAM KVAVRKQRKK IKAKMLGTPE EAESSEDEAG PWILLSDDKG DHPPPPESKI QSFFGLWYRG KAESSEDETS SPAPSKLGGE EEAQPQSPAP DPPCSALHEH LCLGASAAPE A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards