About Coiled-coil domain-containing protein 85A
Coiled-coil domain-containing protein 85A (CCDC85A) is a protein
from Homo sapiens identified by UniProt accession
Q96PX6, 553 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein 85A |
|---|
| UniProt accession | Q96PX6 |
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| Gene | CCDC85A |
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| Organism | Homo sapiens |
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| Length | 553 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (26)
Diseases linked to this target (Open Targets).
- age at menarche · score 0.44
- mathematical ability · score 0.42
- body mass index · score 0.38
- reaction time measurement · score 0.36
- self reported educational attainment · score 0.32
- body height · score 0.31
- gut microbiome measurement · score 0.28
- intelligence · score 0.28
- neurodegenerative disease · score 0.18
- cancer · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96PX6-F1 | alphafold | PREDICTED | 58.50 | — |
Amino-acid sequence (553 residues)
MSKAAGGAAA AAAAAESCSP APAGSSAAPP APVEDLSKVS DEELLQWSKE ELIRSLRRAE AEKVSAMLDH SNLIREVNRR LQLHLGEIRG LKDINQKLQE DNQELRDLCC FLDDDRQKGK RVSREWQRLG RYTAGVMHKE VALYLQKLKD LEVKQEEVVK ENMELKELCV LLDEEKGAGC AGSRCSIDSQ ASLCQLTAST APYVRDVGDG SSTSSTGSTD SPDHHKHHAS SGSPEHLQKP RSEGSPEHSK HRSASPEHPQ KPRACGTPDR PKALKGPSPE HHKPLCKGSP EQQRHPHPGS SPETLPKHVL SGSPEHFQKH RSGSSPEHAR HSGGSPEHLQ KHALGGSLEH LPRARGTSPE HLKQHYGGSP DHKHGGGSGG SGGSGGGSRE GTLRRQAQED GSPHHRNVYS GMNESTLSYV RQLEARVRQL EEENRMLPQA SQNRRQPPTR NSSNMEKGWG SRARRVLQWW QGCRGIGRCL PTLPGSFRLS SGADGSNSSP NSAASFSGHA TPSQQPEPVV HSLKVVWRKL GDAAGSCPGI RQHLSGNQYK GPM
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