About Flagellum-associated coiled-coil domain-containing protein 1
Flagellum-associated coiled-coil domain-containing protein 1 (FLACC1) is a protein
from Homo sapiens identified by UniProt accession
Q96Q35, 445 residues long.
MolForge cross-references it against 0 known binders and
49 disease associations.
Target properties
| Protein name | Flagellum-associated coiled-coil domain-containing protein 1 |
|---|
| UniProt accession | Q96Q35 |
|---|
| Gene | FLACC1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 445 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (49)
Diseases linked to this target (Open Targets).
- platelet count · score 0.42
- serum gamma-glutamyl transferase measurement · score 0.37
- triglyceride measurement · score 0.33
- platelet crit · score 0.33
- neutrophil percentage of leukocytes · score 0.33
- lymphocyte percentage of leukocytes · score 0.32
- rheumatoid arthritis · score 0.32
- basal cell carcinoma · score 0.31
- lymphocyte count · score 0.31
- melanoma · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96Q35-F1 | alphafold | PREDICTED | 75.44 | — |
Amino-acid sequence (445 residues)
MYPNPLIYCT CWDPWNLGPR KLIKTPQLPR KNSTGSSKLT PLVPAPKNHN YLQPTKPVVS PKMKIHSARQ EETNKSFYEV INVSPGYQLV RNREQISVTL GDEMFDRKKR WESEIPDKGR FSRTNIISDL EEQISELTAI IEQMNRDHQS AQKLLSSEMD LRCAEMKQNF ENKNRELKEA HEAELSELEN NYKAALKAEK LAAQEKLEEM GKEYKYLKNM FRTYQDSIYD EMEEKWSKQK AKWKKDEKFE RENILLQQKK KMTKKFEMES GEEDKKINES CSAVFENFIQ EKEELLKQHQ SDTLQLEELR KTKEVPWRRD QINRHWHDVL QQLLLMQVMQ EELHAQALIL ESLNTNLYYT QLELQKEKAI VGNLEKMLQT KFAETEEKYK HTIQILTEEN IHLKQKIISK NEEICEGCSG RLASITVSKD DSDTVQDGSK KGQES
Explore Flagellum-associated coiled-coil domain-containing protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets