About Olfactory receptor 8B4
Olfactory receptor 8B4 (OR8B4) is a protein
from Homo sapiens identified by UniProt accession
Q96RC9, 309 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Olfactory receptor 8B4 |
|---|
| UniProt accession | Q96RC9 |
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| Gene | OR8B4 |
|---|
| Organism | Homo sapiens |
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| Length | 309 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- low grade glioma · score 0.18
- ovarian cancer · score 0.18
- electrocardiography · score 0.12
- self reported educational attainment · score 0.10
- intelligence · score 0.10
- schizophrenia · score 0.10
- gastric carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96RC9-F1 | alphafold | PREDICTED | 89.84 | — |
Amino-acid sequence (309 residues)
MTLRNSSSVT EFILVGLSEQ PELQLPLFLL FLGIYVFTVV GNLGLITLIG INPSLHTPMY FFLFNLSFID LCYSCVFTPK MLNDFVSESI ISYVGCMTQL FFFCFFVNSE CYVLVSMAYD RYVAICNPLL YMVTMSPRVC FLLMFGSYVV GFAGAMAHTG SMLRLTFCDS NVIDHYLCDV LPLLQLSCTS THVSELVFFI VVGVITMLSS ISIVISYALI LSNILCIPSA EGRSKAFSTW GSHIIAVALF FGSGTFTYLT TSFPGSMNHG RFASVFYTNV VPMLNPSIYS LRNKDDKLAL GKTLKRVLF
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