About NudC domain-containing protein 1
NudC domain-containing protein 1 (NUDCD1) is a protein
from Homo sapiens identified by UniProt accession
Q96RS6, 583 residues long.
MolForge cross-references it against 0 known binders and
55 disease associations.
Target properties
| Protein name | NudC domain-containing protein 1 |
|---|
| UniProt accession | Q96RS6 |
|---|
| Gene | NUDCD1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 583 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (55)
Diseases linked to this target (Open Targets).
- intelligence · score 0.26
- schizophrenia · score 0.26
- self reported educational attainment · score 0.26
- platelet crit · score 0.12
- neoplasm · score 0.10
- cancer · score 0.09
- grip strength measurement · score 0.09
- vital capacity · score 0.09
- pachyonychia congenita · score 0.07
- hepatocellular carcinoma · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96RS6-F1 | alphafold | PREDICTED | 86.23 | — |
Amino-acid sequence (583 residues)
MEVAANCSLR VKRPLLDPRF EGYKLSLEPL PCYQLELDAA VAEVKLRDDQ YTLEHMHAFG MYNYLHCDSW YQDSVYYIDT LGRIMNLTVM LDTALGKPRE VFRLPTDLTA CDNRLCASIH FSSSTWVTLS DGTGRLYVIG TGERGNSASE KWEIMFNEEL GDPFIIIHSI SLLNAEEHSI ATLLLRIEKE ELDMKGSGFY VSLEWVTISK KNQDNKKYEI IKRDILRGKS VPHYAAIEPD GNGLMIVSYK SLTFVQAGQD LEENMDEDIS EKIKEPLYYW QQTEDDLTVT IRLPEDSTKE DIQIQFLPDH INIVLKDHQF LEGKLYSSID HESSTWIIKE SNSLEISLIK KNEGLTWPEL VIGDKQGELI RDSAQCAAIA ERLMHLTSEE LNPNPDKEKP PCNAQELEEC DIFFEESSSL CRFDGNTLKT THVVNLGSNQ YLFSVIVDPK EMPCFCLRHD VDALLWQPHS SKQDDMWEHI ATFNALGYVQ ASKRDKKFFA CAPNYSYAAL CECLRRVFIY RQPAPMSTVL YNRKEGRQVG QVAKQQVASL ETNDPILGFQ ATNERLFVLT TKNLFLIKVN TEN
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