P2Y purinoceptor 13 (P2RY13)

Homo sapiens — UniProt Q9BPV8

Gene: P2RY13Homo sapiensSwissProt reviewed

About P2Y purinoceptor 13

P2Y purinoceptor 13 (P2RY13) is a protein from Homo sapiens identified by UniProt accession Q9BPV8, 354 residues long. MolForge cross-references it against 0 known binders and 138 disease associations.

Target properties

Protein nameP2Y purinoceptor 13
UniProt accessionQ9BPV8
GeneP2RY13
OrganismHomo sapiens
Length354 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Approved drugs hitting this target (3)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (138)

Diseases linked to this target (Open Targets).

  • leukocyte count · score 0.28
  • lymphocyte count · score 0.26
  • glioblastoma multiforme · score 0.24
  • ovarian cancer · score 0.23
  • myeloid white cell count · score 0.21
  • neutrophil count · score 0.20
  • platelet-to-lymphocyte ratio · score 0.14
  • monocyte count · score 0.14
  • cutaneous melanoma · score 0.13
  • breast adenocarcinoma · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BPV8-F1alphafoldPREDICTED83.05—

Amino-acid sequence (354 residues)

MTAAIRRQRE LSILPKVTLE AMNTTVMQGF NRSERCPRDT RIVQLVFPAL YTVVFLTGIL LNTLALWVFV HIPSSSTFII YLKNTLVADL IMTLMLPFKI LSDSHLAPWQ LRAFVCRFSS VIFYETMYVG IVLLGLIAFD RFLKIIRPLR NIFLKKPVFA KTVSIFIWFF LFFISLPNTI LSNKEATPSS VKKCASLKGP LGLKWHQMVN NICQFIFWTV FILMLVFYVV IAKKVYDSYR KSKSKDRKNN KKLEGKVFVV VAVFFVCFAP FHFARVPYTH SQTNNKTDCR LQNQLFIAKE TTLFLAATNI CMDPLIYIFL CKKFTEKLPC MQGRKTTASS QENHSSQTDN ITLG

Explore P2Y purinoceptor 13 with MolForge

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Quick facts

UniProtQ9BPV8
GeneP2RY13
OrganismHomo sapiens
Length354
Binders0
Diseases138
View on UniProt