Protein NipSnap homolog 1 (NIPSNAP1)

About Protein NipSnap homolog 1

Protein NipSnap homolog 1 (NIPSNAP1) is a protein from Homo sapiens identified by UniProt accession Q9BPW8, 284 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	Protein NipSnap homolog 1
UniProt accession	Q9BPW8
Gene	NIPSNAP1
Organism	Homo sapiens
Length	284 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (35)

Diseases linked to this target (Open Targets).

mathematical ability · score 0.13
tonsillectomy risk measurement · score 0.09
triglyceride measurement · score 0.08
type 2 diabetes mellitus · score 0.05
cancer · score 0.05
hemoglobin D disease · score 0.04
hemoglobin E disease · score 0.04
Blackfan-Diamond anemia · score 0.04
Adult-onset autosomal recessive sideroblastic anemia · score 0.04
overhydrated hereditary stomatocytosis · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BPW8-F1	alphafold	PREDICTED	82.45	—

Amino-acid sequence (284 residues)

MAPRLCSISV TARRLLGGPG PRAGDVASAA AARFYSKDNE GSWFRSLFVH KVDPRKDAHS TLLSKKETSN LYKIQFHNVK PEYLDAYNSL TEAVLPKLHL DEDYPCSLVG NWNTWYGEQD QAVHLWRFSG GYPALMDCMN KLKNNKEYLE FRRERSQMLL SRRNQLLLEF SFWNEPQPRM GPNIYELRTY KLKPGTMIEW GNNWARAIKY RQENQEAVGG FFSQIGELYV VHHLWAYKDL QSREETRNAA WRKRGWDENV YYTVPLVRHM ESRIMIPLKI SPLQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards