Actin-related protein 2/3 complex subunit 5-like…

About Actin-related protein 2/3 complex subunit 5-like protein

Actin-related protein 2/3 complex subunit 5-like protein (ARPC5L) is a protein from Homo sapiens identified by UniProt accession Q9BPX5, 153 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Actin-related protein 2/3 complex subunit 5-like protein
UniProt accession	Q9BPX5
Gene	ARPC5L
Organism	Homo sapiens
Length	153 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.51
Alzheimer disease · score 0.35
multiple sclerosis · score 0.35
Parkinson disease · score 0.35
lysosomal storage disease · score 0.35
grip strength measurement · score 0.07
testosterone measurement · score 0.07
Griscelli syndrome type 3 · score 0.06
Ataxia - oculomotor apraxia type 1 · score 0.06
Griscelli disease · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BPX5-F1	alphafold	PREDICTED	89.03	—

Amino-acid sequence (153 residues)

MARNTLSSRF RRVDIDEFDE NKFVDEQEEA AAAAAEPGPD PSEVDGLLRQ GDMLRAFHAA LRNSPVNTKN QAVKERAQGV VLKVLTNFKS SEIEQAVQSL DRNGVDLLMK YIYKGFEKPT ENSSAVLLQW HEKALAVGGL GSIIRVLTAR KTV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Actin-related protein 2/3 complex subunit 5-like protein (ARPC5L)