Coiled-coil domain-containing protein 3 (CCDC3)

About Coiled-coil domain-containing protein 3

Coiled-coil domain-containing protein 3 (CCDC3) is a protein from Homo sapiens identified by UniProt accession Q9BQI4, 270 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.

Target properties

Protein name	Coiled-coil domain-containing protein 3
UniProt accession	Q9BQI4
Gene	CCDC3
Organism	Homo sapiens
Length	270 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (73)

Diseases linked to this target (Open Targets).

body height · score 0.51
alcohol consumption measurement · score 0.45
wellbeing measurement · score 0.45
BMI-adjusted waist circumference · score 0.39
t-tau measurement · score 0.33
sitting height measurement · score 0.31
appendicular lean mass · score 0.31
BMI-adjusted hip circumference · score 0.30
forced expiratory volume · score 0.26
neurodegenerative disease · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BQI4-F1	alphafold	PREDICTED	75.44	—

Amino-acid sequence (270 residues)

MLRQLLLAAL CLAGPPAPAR ACQLPSEWRP LSEGCRAELA ETIVYARVLA LHPEAPGLYN HLPWQYHAGQ GGLFYSAEVE MLCDQAWGSM LEVPAGSRLN LTGLGYFSCH SHTVVQDYSY FFFLRMDENY NLLPHGVNFQ DAIFPDTQEN RRMFSSLFQF SNCSQGQQLA TFSSDWEIQE DSRLMCSSVQ KALFEEEDHV KKLQQKVATL EKRNRQLRER VKKVKRSLRQ ARKKGRHLEL ANQKLSEKLA AGALPHINAR GPVRPPYLRG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards