Sulfotransferase 4A1 (SULT4A1)

About Sulfotransferase 4A1

Sulfotransferase 4A1 (SULT4A1) is a protein from Homo sapiens identified by UniProt accession Q9BR01, 284 residues long. MolForge cross-references it against 0 known binders and 224 disease associations.

Target properties

Protein name	Sulfotransferase 4A1
UniProt accession	Q9BR01
Gene	SULT4A1
Organism	Homo sapiens
Length	284 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (224)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
self reported educational attainment · score 0.10
Unverricht-Lundborg disease · score 0.07
Spinocerebellar ataxia type 40 · score 0.07
familial infantile myoclonic epilepsy · score 0.07
infantile convulsions and choreoathetosis · score 0.07
juvenile myoclonic epilepsy · score 0.07
generalised epilepsy · score 0.07
spinocerebellar ataxia type 23 · score 0.06
spinocerebellar ataxia type 20 · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BR01-F1	alphafold	PREDICTED	86.82	—

Amino-acid sequence (284 residues)

MAESEAETPS TPGEFESKYF EFHGVRLPPF CRGKMEEIAN FPVRPSDVWI VTYPKSGTSL LQEVVYLVSQ GADPDEIGLM NIDEQLPVLE YPQPGLDIIK ELTSPRLIKS HLPYRFLPSD LHNGDSKVIY MARNPKDLVV SYYQFHRSLR TMSYRGTFQE FCRRFMNDKL GYGSWFEHVQ EFWEHRMDSN VLFLKYEDMH RDLVTMVEQL ARFLGVSCDK AQLEALTEHC HQLVDQCCNA EALPVGRGRV GLWKDIFTVS MNEKFDLVYK QKMGKCDLTF DFYL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards