Neuralized-like protein 2 (NEURL2)

About Neuralized-like protein 2

Neuralized-like protein 2 (NEURL2) is a protein from Homo sapiens identified by UniProt accession Q9BR09, 285 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.

Target properties

Protein name	Neuralized-like protein 2
UniProt accession	Q9BR09
Gene	NEURL2
Organism	Homo sapiens
Length	285 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (46)

Diseases linked to this target (Open Targets).

free cholesterol to total lipids in large HDL percentage · score 0.32
concentration of large HDL particles measurement · score 0.31
free cholesterol in very large HDL measurement · score 0.31
cholesteryl ester measurement · score 0.29
cholesterol to total lipids in large HDL percentage · score 0.28
total lipids in very large HDL measurement · score 0.27
cholesterol in very large HDL measurement · score 0.27
phospholipids in very large HDL measurement · score 0.27
high density lipoprotein particle size measurement · score 0.19
phospholipids:total lipids ratio · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BR09-F1	alphafold	PREDICTED	83.03	—

Amino-acid sequence (285 residues)

MAAASEPVDS GALWGLERPE PPPTRFHRVH GANIRVDPSG TRATRVESFA HGVCFSREPL APGQVFLVEI EEKELGWCGH LRLGLTALDP ASLAPVPEFS LPDLVNLGHT WVFAITRHHN RVPREGRPEA EAAAPSRPPT LLVEPYLRIE QFRIPRDRLV GRSRPGLYSH LLDQLYELNV LPPTARRSRL GVLFCPRPDG TADMHIIING EDMGPSARGL PAAQPLYAVV DVFASTKSVR LVQLEYGLPS LQTLCRLVIQ RSMVHRLAID GLHLPKELKD FCKYE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards